In 2021, 173 firms conducted biotechnology activities, which constitutes a decrease by 2.3% in comparison to the previous year. Biotechnology intramural expenditures incurred by firms amounted to PLN 1380.9 million and increased by 13.2% on an annual basis. In 2021, 3953 persons were employed in biotechnology in firms. Biotechnology research and experimental development was conducted by 217 entities, that is, by 4.4% less in comparison with the previous year. Biotechnology R&D intramural expenditures amounted to PLN 1184.7 million and increased by 8.7% annually. 8202 persons were involved in biotechnology research and experimental development.